SPEAKER: Zhe WANG   Tenure-track Associate Professor, Ph.D. Supervisor, PI Department of Animal Science, SAB

TIME ：13:30-14:15 Dec 23 2020 (Wednesday)

VENUE：Room 104, Building B, School of Agriculture and Biology

ORGANIZER：Office of Discipline and Science & Technology, SAB; Young Teachers Association, SAB

TITTLE: Application of Metabolomics in Combating Mycobacterium Infection

ABSTRACT: 

Mycobacteria genus includes many bacterial pathogens that can cause serious diseases in mammals. Among them, Mycobacteria tuberculosis can infect human and animal, causing tuberculosis (TB). China is still one of the countries with the worst TB epidemics. Meanwhile, the problem of drug resistance caused by antibiotic abuse is increasing year by year, therefore the demand for novel antibiotics is becoming more and more urgent. Metabolomics is one of the newest Omics techniques, and it is being widely used now. Particularly, it can help us understand mycobacteria's unique physiological characteristics of "slow growth, long non-replication phase, and strong resistance" from the perspective of system biology. At the same time, metabolomics approach can assist us in antimicrobial discovery through more quickly identifying novel drug targets, understanding the mechanisms of drug action and resistance, and finding more effective drug combinations.